Hormone Therapy

Bioidentical Hormone Therapy in San Diego, CA

Comprehensive bioidentical hormone therapy in San Diego — estrogen, progesterone, testosterone, thyroid, and adrenal support. Personalized HRT by Dr. Joseph Dubroff, N.D.

Bioidentical hormone therapy San Diego
The Problem

"My Doctor Says My Labs Are Normal. But I Don't Feel Normal."

If you've been told your labs are within range while you're still feeling exhausted, foggy, anxious, sleeping poorly, gaining weight you can't lose, or noticing changes in your libido, mood, or strength — you are not imagining it. The conventional reference ranges most doctors use to say "you're fine" are extraordinarily wide, and they were built around populations of mostly older, mostly unwell people.

Optimal isn't the same as normal. Dr. Dubroff orders comprehensive hormone, thyroid, and adrenal panels — including the markers most primary care physicians don't run — and reads them against optimal ranges, not just whatever your insurance considers acceptable.

Persistent FatigueYou sleep eight hours and still feel exhausted. Coffee stops working.
Brain Fog & MemoryWord recall, focus, and short-term memory aren't what they used to be.
Hot Flashes & Night SweatsPerimenopause and menopause symptoms disrupting sleep and quality of life.
Stubborn Weight GainEspecially around the midsection, despite no change in diet or exercise.
Mood, Anxiety & IrritabilitySudden shifts in temperament, sadness, or anxiety without clear cause.
Low Libido & EnergyDecreased sex drive, reduced strength, sluggish recovery from workouts.
Cold Hands & FeetEven when room temperature is fine — often a thyroid signal.
Sleep DisruptionWaking at 2–4 AM. Difficulty falling back asleep. Often cortisol-driven.
The Approach

What Bioidentical Hormone Therapy Actually Is.

Bioidentical hormones are molecularly identical to the hormones your body makes naturally. Unlike synthetic hormone medications — which differ slightly in molecular structure and produce a different cascade of effects — bioidentical hormones bind to the same receptors and behave the same way as your endogenous hormones.

This matters because it means a smaller, more targeted dose can produce a real clinical effect, and the side-effect profile is markedly different. Dr. Dubroff doesn't prescribe a one-size-fits-all protocol. Every plan is built from your specific lab work, your symptoms, your age, and your goals.

Bioidentical HRT

Same molecule as your body's own

Compounded estradiol, progesterone, testosterone — molecularly identical to natural hormones. Personalized dosing based on your labs and how you actually feel.

Conventional Synthetic HRT

Patented, slightly modified molecules

Synthetic progestins and conjugated estrogens. Different molecular structures, different receptor effects, broader side-effect profile, fixed-dose protocols.

Specialties

Seven Hormone Pathways. One Comprehensive Practice.

Most clinics treat one hormone in isolation. Dr. Dubroff treats your endocrine system as a whole — because your hormones are connected, and treating one without the others almost always misses the root cause.

— 01

Perimenopause & Menopause

Hot flashes, night sweats, sleep disruption, mood changes, libido loss, weight gain. Comprehensive bioidentical estrogen and progesterone protocols matched to where you are in the transition.

— 02

Thyroid Treatment

Undiagnosed hypothyroid, reverse T3, free T3, free T4. If your doctor said your labs are "normal" but you're cold, exhausted, and gaining weight — there's almost always more to the story.

— 03

Adrenal Fatigue & Cortisol

Chronic stress, burnout, 2 AM wakeups, afternoon crashes. Comprehensive cortisol and DHEA assessment — and protocols to actually rebuild adrenal function instead of medicating around it.

— 04

Testosterone Therapy

For men with low T symptoms — fatigue, low libido, reduced strength, mood, brain fog. Bioidentical testosterone protocols that go beyond a number on a lab and address the full hormonal picture.

— 05

Estrogen Therapy

Estradiol, estriol, and combination protocols for women experiencing the full range of estrogen-related symptoms — from menopause to surgical hormone loss to chronic estrogen dominance issues.

— 06

Progesterone Therapy

The "calming" hormone. Bioidentical oral and topical progesterone for sleep, anxiety, perimenopause symptoms, and balanced HRT — never synthetic progestins.

— 07

Enclomiphene

For men who want the benefits of testosterone optimization without suppressing their natural production or fertility. Enclomiphene citrate stimulates endogenous testosterone — a different path to the same goal.

The Process

How Hormone Care Actually Works.

01

Comprehensive Lab Panel

Far more than a basic hormone panel. Dr. Dubroff orders the markers most primary care doctors skip — including reverse T3, free testosterone, DHEA-S, full cortisol, and SHBG — to build a real picture of your endocrine system.

02

Two-Hour Intake

Your first visit is two hours, in your home. Dr. Dubroff reviews labs alongside your full health history, lifestyle, sleep, stress, and what your symptoms are actually telling us. The protocol comes from this conversation — not a template.

03

Ongoing Adjustment

Hormone optimization is iterative. Dr. Dubroff retests, refines doses, and adjusts protocols as your body responds. Follow-up calls about your existing plan are always free — you have direct access to your doctor, not a portal.

Common Questions

Hormone Therapy FAQs

What's the difference between bioidentical and synthetic HRT?+
Bioidentical hormones are molecularly identical to the hormones your body makes naturally. Synthetic hormones (like Premarin or Provera) are slightly different molecules that bind differently to receptors and produce different downstream effects. Bioidentical hormones generally allow for more precise dosing and a different side-effect profile, particularly with progesterone vs. synthetic progestins.
My doctor said my thyroid labs are normal — could I still have a thyroid problem?+
Yes, very often. Most primary care doctors only run TSH and sometimes free T4. They miss reverse T3, free T3, thyroid antibodies, and don't read the labs against optimal ranges. Patients with classic hypothyroid symptoms whose TSH is "in range" frequently turn out to have meaningful thyroid issues that respond well to treatment once they're properly evaluated.
Is bioidentical HRT safe?+
For most patients, when properly dosed and monitored, yes. Like any hormone therapy, it carries risks and benefits that depend on your individual health history. Dr. Dubroff reviews your medical history thoroughly, monitors lab work, and adjusts protocols as needed. Anyone with a history of hormone-sensitive cancer or specific contraindications would not be a candidate for certain therapies.
How long until I feel better?+
It depends on what's being treated. Some patients notice improvement in sleep, mood, or energy within 2-4 weeks. Other improvements — like body composition changes, libido, or full thyroid optimization — typically take 3-6 months. Hormone optimization is a process, not an event, and Dr. Dubroff refines the protocol as your body responds.
Do you treat both men and women?+
Yes. Dr. Dubroff treats both men and women across the full range of hormonal concerns — perimenopause and menopause, low testosterone, thyroid disorders, adrenal dysfunction, and chronic fatigue with a hormonal component.
Where are the hormones sourced?+
Dr. Dubroff prescribes through licensed compounding pharmacies that meet rigorous quality and safety standards. Compounding allows for personalized dosing and delivery methods (oral, topical, injection, pellet) tailored to each patient — something fixed-dose retail prescriptions can't do.
Does insurance cover hormone therapy?+
Coverage varies. Some lab work and standard hormone medications may be covered through your insurance with a prescription. Compounded bioidentical hormones are usually not covered. Dr. Dubroff's consultations are fee-for-service; we can provide a superbill for possible reimbursement.
Get Started

Stop Settling for "Within Range."

Book a free consultation. Dr. Dubroff will tell you what comprehensive hormone testing actually looks like — and whether bioidentical HRT is likely to help you.