Before GLP-1 medications dominated the weight-loss landscape, MIC injections — "skinny shots" — were one of the most widely used metabolic adjuncts in medical weight-loss practice. They aren't a weight-loss drug in the way Mounjaro or Ozempic is. They don't suppress appetite or slow gastric emptying. What they do is support the metabolic machinery that processes fat — methionine, inositol, and choline are all involved in fat metabolism, liver function, and energy production.
In a clinical weight-loss context, MIC injections are typically used in one of two ways: as a supportive adjunct alongside a GLP-1 protocol or HCG program, providing nutrient support during caloric reduction and helping the body process mobilized fat efficiently — or as a standalone metabolic support for patients who are already doing the diet-and-exercise work but want additional nutritional reinforcement for liver function, energy, and fat metabolism.
They're an old-school tool with a useful place in modern protocols. Not a miracle, not a marketing claim — just an established lipotropic injection with a meaningful supportive role when used appropriately.
"MIC" stands for the three core compounds. Each plays a distinct role in fat metabolism and liver function. Together they form the basic MIC formulation, often combined with additional B vitamins or supportive nutrients depending on the formulation.
An essential amino acid the body uses for liver function, fat metabolism, and detoxification pathways. Methionine helps the body break down and process fats in the liver, supporting how efficiently fat is mobilized and used for energy rather than stored.
A compound closely related to the B vitamin family that supports insulin signaling, fat metabolism, and the structure of cell membranes. Particularly relevant for patients with insulin resistance, PCOS, or metabolic syndrome features — inositol has documented effects on insulin sensitivity.
An essential nutrient for liver function and fat transport. Choline is required to move fat out of the liver and into the bloodstream where it can be used for energy. Choline deficiency is associated with fatty liver accumulation, which is why it's a key player in lipotropic protocols.
MIC injections aren't a replacement for serious weight-loss interventions — and Dr. Dubroff doesn't market them as one. They fit specific clinical situations particularly well:
Book a free consultation. Dr. Dubroff will tell you whether MIC injections make sense for your weight-loss program — or whether another tool is the better fit for your situation.